The author examines the scientific dimension of an applied research project in the Louvre Museum. Framed within the museum’s plan to reshape communication with museum visitors, the study had a theoretical framework and several mediation tools that support the complexity of a world of writing involving multiple issues. For this purpose, going beyond interventions limited to museology, the study identified and integrated various forms of writing museum texts into a reconsideration of the place of the institution in the public sphere and the multiple rationalities of communication underlying its interventions. The translation of this model into a mediation apparatus, grounded in the reality of the institution and its audience, required a dialogue with the mediator team in order to create documentary and media formats, for adopting a common frame of action, and to adapt the forms of communication to local and specific purposes simultaneously, i.e., mediating mediation. The opportunity exists to reflect on the economy of forms of writing in the museum, the various meanings given by actors to mediation, and the sharing of knowledge among mediators and researchers.